The Futurama Archive - Oh Futurama, how I love thee. This was probably the first Futurama site I ever found, and I can safely say it is the best, content wise. The multimedia is a little lacking, but everything else is a class act.
The Futurama Outlet - Probably the other greatest Futurama site out there. They even have an MP3 of the "Robot Hell" song! Instant cool point. Ladies and gentlemen, if it's multimedia you be needin', this be the site, g'yar.

The Dilbert Zone - I don't care what critics/idiots like Norman Solomon and that Village Voice guy say, Dilbert rocks. The official site, and it is a kick booty one at that. I'm a card carrying member of the DNRC, so if you want some serious brownie points, say good things about Dogbert and Homer in your emails. Oh, and the show is GREAT. Probably the third best on TV, next to the Simpsons and Futurama.
Garfield.com - Garfield is one of my other all time comic strips. This is a pretty sweet site, my major complaint is the imagemap, which takes FOREVER to load. Other than that, a nifty site, plus it's got its own free email service, G-Mail. Yaaaaahooo.
The Official Peanuts Homepage - Ever since I was a kid, I loved the adventures of Snoopy and the gang, and I'd like to say I believe Charles Schulz is a cartooning legend. The site's pretty cool too. Lotsa neat stuff.

The Official Late Late Show with Craig Kilborn Website - Ever since I saw Kilborn on the Daily Show, I've firmly believed he was one of the funniest guys on TV. Go here and may you find much humor.
The Official Late Show with David Letterman Website - Letterman never fails to crack me up either. Probably this site's biggest draw is the Top 10 archive. Hee hee.